Feasibility study to investigate caking in washing powder formulations using a Freeman FT4 powder rheometer

Stress and strain rate analysis of the FT4 Powder Rheometer

The Freeman FT4 Powder Rheometer has been reported to describe well the powder flow behaviour in instances where other techniques fail. We use DEM to simulate the FT4 operation for slightly cohesive large glass beads at a range of strain rates. The curved impeller is shown to be beneficial in comparison to a flat blade as the variation of shear stress across the blade is reduced. The shear stre...

Analysis of the dynamics of the FT4 powder rheometer

Available online 24 April 2015

Development of a Reproducible Powder Characterization Method Using a Powder Rheometer

In this study, a powder rheometer was used to measure flow characteristics of two pharmaceutical model powders. Precise measurements were obtained for one of the model powders whereas the results were less precise for the second powder. In conclusion, further work is needed to increase the mechanistic understanding of powder rheological measurements. INTRODUCTION Modern pharmaceuticals are prim...

Particulate Interactions in Dry Powder Formulations for Inhalation Particulate Interactions in Dry Powder Formulations for Inhalation

Using Neutron Diffraction to Investigate Texture Evolution During Consolidation of Deuterated Triaminotrinitrobenzene (d-TATB) Explosive Powder

Triaminotrinitrobenzene (TATB) is a highly anisotropic molecular crystal used in several plastic-bonded explosive (PBX) formulations. A complete understanding of the orientation distribution of TATB particles throughout a PBX charge is required to understand spatially variable, anisotropic macroscale properties of the charge. Although texture of these materials can be measured after they have b...